Colorectal cancer CRC is a major health problem in the Western world. The diagnostic process is a challenge in all health systems for many reasons: There are often no specific symptoms; lower abdominal symptoms are very common and mostly related to non-neoplastic diseases, not CRC; diagnosis of CRC is mainly based on colonoscopy, an invasive procedure; and the resource for diagnosis is usually scarce. Furthermore, the available predictive models for CRC are based on the evaluation of symptoms, and their diagnostic accuracy is limited. Moreover, diagnosis is a complex process involving a sequence of events related to the patient, the initial consulting physician and the health system.
A ten language instruction sheet is provided to assist patients or healthcare professionals with the proper use of the kits at home or in the healthcare setting. The diagnosis of intestinal parasitic infection is confirmed by the recovery of helminth larvae and eggs, protozoan trophozoites and cysts, coccidian oocysts, and microsporidian spores. The ability to detect and identify intestinal parasites in fresh stool specimen depends on immediate collection, transportation, and examination by the laboratory; often, these time requirements from passage of the specimen to examination cannot be guaranteed. Junod, in , described the use of SAF sodium acetate-acetic acid-formalin as a multipurpose means of preserving intestinal parasites. Scholten and Yang, in a study of more than specimens, confirmed the suitability of SAF for routine use in the clinical parasitology laboratory. Proper use of the SAF kits assures the preservation and proper identification of all stages of intestinal parasites. SAF allows permanent stains and concentration procedures to be performed on a single sample.
Do diagnostic and treatment delays for colorectal cancer increase risk of death?
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We hypothesized that longer delays would be associated with a greater risk of death. We defined diagnostic and treatment delays, respectively, as days between 1 initial medical consult for CRC symptoms and pathologically-confirmed diagnosis maximum: days and 2 pathologically-confirmed diagnosis and treatment maximum: days. Cases CRC deaths and controls deaths due to other causes or censored were matched on survival time. Logistic regression analyses adjusted for sociodemographic, tumor, and treatment factors.